Publications

2026

Progressive coevolution of the yeast centromere and kinetochore
Helsen J, Ramachandran K, Sherlock G, Dey G
Nature 651 (8107), 1012-1019

2024

Spindle architecture constrains karyotype evolution
Helsen J, Reza H, Carvalho R, Sherlock G, Dey G
Nature Cell Biology 26, 1496–1503

2023

Experimental evolution for cell biology
Helsen J, Sherlock G, Dey G
Trends in Cell Biology 33 (11), 903-912

2022

Single-cell RNA sequencing in yeast using the 10x Genomics chromium device
Vermeersch L, Jariani A, Helsen J, Heineike BM, Verstrepen KJ
Yeast Functional Genomics: Methods and Protocols, 3-20

2021

Experimental evolution to understand the interplay between genetics and adaptation
Helsen J, Jelier R
Evolutionary Systems Biology: Advances, Questions, and Opportunities, 115-134

2020

Gene loss predictably drives evolutionary adaptation
Helsen J, Voordeckers K, Vanderwaeren L, Santermans T, Tsontaki M, Verstrepen KJ, Jelier R
Molecular Biology and Evolution 37 (10), 2989-3002

2019

Network hubs affect evolvability
Helsen J, Frickel J, Jelier R, Verstrepen KJ
PLoS biology 17 (1), e3000111